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Novel psoralen derivatives as anti-breast cancer agents and their light-activated cytotoxicity against HER2 positive breast cancer cells

Psoralen derivatives are well known for their unique phototoxicity and also exhibits promising anti-breast cancer activity both in the presence and the absence of UVA irradiation. However, the structure–activity relationship on this scaffold remains lacking. Herein, a series of psoralen derivatives...

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Detalles Bibliográficos
Autores principales: Aekrungrueangkit, Chiphada, Wangngae, Sirilak, Kamkaew, Anyanee, Ardkhean, Ruchuta, Thongnest, Sanit, Boonsombat, Jutatip, Ruchirawat, Somsak, Khotavivattana, Tanatorn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9356065/
https://www.ncbi.nlm.nih.gov/pubmed/35931753
http://dx.doi.org/10.1038/s41598-022-17625-x