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Compartmentalized regulation of NAD(+) by Di (2-ethyl-hexyl) phthalate induces DNA damage in placental trophoblast
Di (2-ethyl-hexyl) phthalate (DEHP) is a wildly used plasticizer. Maternal exposure to DEHP during pregnancy blocks the placental cell cycle at the G2/M phase by reducing the efficiency of the DNA repair pathways and affects the health of offsprings. However, the mechanism by which DEHP inhibits the...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9356100/ https://www.ncbi.nlm.nih.gov/pubmed/35926314 http://dx.doi.org/10.1016/j.redox.2022.102414 |