Cargando…

Compartmentalized regulation of NAD(+) by Di (2-ethyl-hexyl) phthalate induces DNA damage in placental trophoblast

Di (2-ethyl-hexyl) phthalate (DEHP) is a wildly used plasticizer. Maternal exposure to DEHP during pregnancy blocks the placental cell cycle at the G2/M phase by reducing the efficiency of the DNA repair pathways and affects the health of offsprings. However, the mechanism by which DEHP inhibits the...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhao, Shuai, Hong, Yun, Liang, Yue-yue, Li, Xiao-lu, Shen, Jiang-chuan, Sun, Cong-cong, Chu, Ling-luo, Hu, Jie, Wang, Hua, Xu, De-xiang, Zhang, Shi-chen, Xu, Dou-dou, Xu, Tao, Zhao, Ling-li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9356100/
https://www.ncbi.nlm.nih.gov/pubmed/35926314
http://dx.doi.org/10.1016/j.redox.2022.102414