System-wide analyses reveal essential roles of N-terminal protein modification in bacterial membrane integrity

The removal of the N-terminal formyl group on nascent proteins by peptide deformylase (PDF) is the most prevalent protein modification in bacteria. PDF is a critical target of antibiotic development; however, its role in bacterial physiology remains a long-standing question. This work used the time-...

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Detalles Bibliográficos
Autores principales: Yang, Chien-I, Zhu, Zikun, Jones, Jeffrey J., Lomenick, Brett, Chou, Tsui-Fen, Shan, Shu-ou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9356101/
https://www.ncbi.nlm.nih.gov/pubmed/35942092
http://dx.doi.org/10.1016/j.isci.2022.104756

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9356101/
https://www.ncbi.nlm.nih.gov/pubmed/35942092
http://dx.doi.org/10.1016/j.isci.2022.104756

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