Co-targeting of specific epigenetic regulators in combination with CDC7 potently inhibit melanoma growth

Melanoma is a highly aggressive skin cancer that frequently metastasizes, but current therapies only benefit some patients. Here, we demonstrate that the serine/threonine kinase cell division cycle 7 (CDC7) is overexpressed in melanoma, and patients with higher expression have shorter survival. Tran...

Descripción completa

Detalles Bibliográficos
Autores principales: Chava, Suresh, Bugide, Suresh, Malvi, Parmanand, Gupta, Romi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9356103/
https://www.ncbi.nlm.nih.gov/pubmed/35942091
http://dx.doi.org/10.1016/j.isci.2022.104752

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9356103/
https://www.ncbi.nlm.nih.gov/pubmed/35942091
http://dx.doi.org/10.1016/j.isci.2022.104752

Ejemplares similares