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Co-targeting of specific epigenetic regulators in combination with CDC7 potently inhibit melanoma growth
Melanoma is a highly aggressive skin cancer that frequently metastasizes, but current therapies only benefit some patients. Here, we demonstrate that the serine/threonine kinase cell division cycle 7 (CDC7) is overexpressed in melanoma, and patients with higher expression have shorter survival. Tran...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9356103/ https://www.ncbi.nlm.nih.gov/pubmed/35942091 http://dx.doi.org/10.1016/j.isci.2022.104752 |