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Metabolic reprogramming from glycolysis to fatty acid uptake and beta-oxidation in platinum-resistant cancer cells

Increased glycolysis is considered as a hallmark of cancer. Yet, cancer cell metabolic reprograming during therapeutic resistance development is under-studied. Here, through high-throughput stimulated Raman scattering imaging and single cell analysis, we find that cisplatin-resistant cells exhibit i...

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Detalles Bibliográficos
Autores principales: Tan, Yuying, Li, Junjie, Zhao, Guangyuan, Huang, Kai-Chih, Cardenas, Horacio, Wang, Yinu, Matei, Daniela, Cheng, Ji-Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9356138/
https://www.ncbi.nlm.nih.gov/pubmed/35931676
http://dx.doi.org/10.1038/s41467-022-32101-w