Hypoxia-hindered methylation of PTGIS in endometrial stromal cells accelerates endometriosis progression by inducing CD16(−) NK-cell differentiation

Prostacyclin (PGI(2)) plays key roles in shaping the immune microenvironment and modulating vasodilation, whereas its contribution to endometriosis (EMs) remains largely unclear. Our study suggested that prostacyclin synthase (PTGIS)-dependent PGI(2) signaling was significantly activated in EMs, whi...

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Detalles Bibliográficos
Autores principales: Peng, Haiyan, Weng, Lichun, Lei, Shating, Hou, Shuhui, Yang, Shaoliang, Li, Mingqing, Zhao, Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9356144/
https://www.ncbi.nlm.nih.gov/pubmed/35781537
http://dx.doi.org/10.1038/s12276-022-00793-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9356144/
https://www.ncbi.nlm.nih.gov/pubmed/35781537
http://dx.doi.org/10.1038/s12276-022-00793-1

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