Protocol to stimulate and delineate alternative lengthening of telomeres in human U2OS cells

Alternative lengthening of telomeres (ALT) is a telomerase-independent but recombination-dependent pathway that maintains telomeres. Here, we describe a protocol to stimulate the formation of ALT-associated PML bodies (APBs) and ALT activity by tethering PML-IV to telomeres in human U2OS cells. Thro...

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Detalles Bibliográficos
Autores principales: Zhang, Jia-Min, Zou, Lee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9356160/
https://www.ncbi.nlm.nih.gov/pubmed/35942347
http://dx.doi.org/10.1016/j.xpro.2022.101594

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9356160/
https://www.ncbi.nlm.nih.gov/pubmed/35942347
http://dx.doi.org/10.1016/j.xpro.2022.101594

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