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Experimental and computational workflow for the analysis of tRNA pools from eukaryotic cells by mim-tRNAseq
Quantifying tRNAs is crucial for understanding how they regulate mRNA translation but is hampered by their extensive sequence similarity and premature termination of reverse transcription at multiple modified nucleotides. Here, we describe the use of modification-induced misincorporation tRNA sequen...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9356165/ https://www.ncbi.nlm.nih.gov/pubmed/35942339 http://dx.doi.org/10.1016/j.xpro.2022.101579 |