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Therapeutic knockdown of miR-320 improves deteriorated cardiac function in a pre-clinical model of non-ischemic diabetic heart disease

Non-ischemic diabetic heart disease (NiDHD) is characterized by diastolic dysfunction and decreased or preserved systolic function, eventually resulting in heart failure. Accelerated apoptotic cell death because of alteration of molecular signaling pathways due to dysregulation in microRNAs (miRNAs)...

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Detalles Bibliográficos
Autores principales: Ghosh, Nilanjan, Fenton, Sonya, van Hout, Isabelle, Jones, Gregory T., Coffey, Sean, Williams, Michael J.A., Sugunesegran, Ramanen, Parry, Dominic, Davis, Philip, Schwenke, Daryl O., Chatterjee, Anirudha, Katare, Rajesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9356207/
https://www.ncbi.nlm.nih.gov/pubmed/35950211
http://dx.doi.org/10.1016/j.omtn.2022.07.007