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The permeation of potassium ions through the lipid scrambling path of the membrane protein nhTMEM16

The TMEM16 family of transmembrane proteins includes Ca(2+)-activated phospholipid scramblases (PLS) that can also function as non-selective ion channels. Extensive structural and functional studies have established that a membrane-exposed hydrophilic groove in TMEM16 PLS can serve as a translocatio...

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Detalles Bibliográficos
Autores principales: Cheng, Xiaolu, Khelashvili, George, Weinstein, Harel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9356224/
https://www.ncbi.nlm.nih.gov/pubmed/35942471
http://dx.doi.org/10.3389/fmolb.2022.903972