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Semaphorin 4D is upregulated in neurons of diseased brains and triggers astrocyte reactivity

BACKGROUND: The close interaction and interdependence of astrocytes and neurons allows for the possibility that astrocyte dysfunction contributes to and amplifies neurodegenerative pathology. Molecular pathways that trigger reactive astrocytes may represent important targets to preserve normal homeo...

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Detalles Bibliográficos
Autores principales: Evans, Elizabeth E., Mishra, Vikas, Mallow, Crystal, Gersz, Elaine M., Balch, Leslie, Howell, Alan, Reilly, Christine, Smith, Ernest S., Fisher, Terrence L., Zauderer, Maurice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9356477/
https://www.ncbi.nlm.nih.gov/pubmed/35933420
http://dx.doi.org/10.1186/s12974-022-02509-8