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Metabolic engineering of the l-serine biosynthetic pathway improves glutathione production in Saccharomyces cerevisiae

BACKGROUND: Glutathione is a valuable tri-peptide that is industrially produced by fermentation using the yeast Saccharomyces cerevisiae, and is widely used in the pharmaceutical, food, and cosmetic industries. It has been reported that addition of l-serine (l-Ser) is effective at increasing the int...

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Detalles Bibliográficos
Autores principales: Kobayashi, Jyumpei, Sasaki, Daisuke, Hara, Kiyotaka Y., Hasunuma, Tomohisa, Kondo, Akihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9356478/
https://www.ncbi.nlm.nih.gov/pubmed/35933377
http://dx.doi.org/10.1186/s12934-022-01880-8