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The role of the aging microenvironment on the fate of PDGFRβ lineage cells in skeletal muscle repair

BACKGROUND: During aging, perturbation of muscle progenitor cell (MPC) constituents leads to progressive loss of muscle mass and accumulation of adipose and fibrotic tissue. Mesenchymal stem cells (MSCs) give rise to adipocytes and fibroblasts that accumulate in injured and pathological skeletal mus...

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Detalles Bibliográficos
Autores principales: Lu, Aiping, Tseng, Chieh, Guo, Ping, Gao, Zhanguo, Whitney, Kaitlyn E., Kolonin, Mikhail G., Huard, Johnny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9356493/
https://www.ncbi.nlm.nih.gov/pubmed/35932084
http://dx.doi.org/10.1186/s13287-022-03072-y