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The role of the aging microenvironment on the fate of PDGFRβ lineage cells in skeletal muscle repair
BACKGROUND: During aging, perturbation of muscle progenitor cell (MPC) constituents leads to progressive loss of muscle mass and accumulation of adipose and fibrotic tissue. Mesenchymal stem cells (MSCs) give rise to adipocytes and fibroblasts that accumulate in injured and pathological skeletal mus...
Autores principales: | Lu, Aiping, Tseng, Chieh, Guo, Ping, Gao, Zhanguo, Whitney, Kaitlyn E., Kolonin, Mikhail G., Huard, Johnny |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9356493/ https://www.ncbi.nlm.nih.gov/pubmed/35932084 http://dx.doi.org/10.1186/s13287-022-03072-y |
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