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Transmembrane Protein ANTXR1 Regulates γ-Globin Expression by Targeting the Wnt/β-Catenin Signaling Pathway

Reactivation of fetal hemoglobin (HbF, α2γ2) alleviates clinical symptoms in patients with β-thalassemia and sickle cell disease, although the regulatory mechanisms of γ-globin expression have not yet been fully elucidated. Recent studies found that interfering with the expression of the membrane pr...

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Detalles Bibliográficos
Autores principales: Jin, Tingting, Zhang, Zhaojun, Han, Yuanyuan, Li, Di, Liu, Juan, Jiang, Minmin, Zhu, Junwei, Kurita, Ryo, Nakamura, Yukio, Hu, Fangfang, Xu, Yongjie, Fang, Xiangdong, Huang, Shengwen, Sun, Zhaolin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9356848/
https://www.ncbi.nlm.nih.gov/pubmed/35942209
http://dx.doi.org/10.1155/2022/8440422