Circular RNA MELK Promotes Chondrocyte Apoptosis and Inhibits Autophagy in Osteoarthritis by Regulating MYD88/NF-κB Signaling Axis through MicroRNA-497-5p

Osteoarthritis (OA) is a rheumatic disease and its pathogenesis involves the dysregulation of noncoding RNAs. Therefore, the regulatory mechanism of circular RNA MELK (circMELK) was specified in this work. OA human cartilage tissue was collected, and circMELK, miR-497-5p, and myeloid differentiation...

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Detalles Bibliográficos
Autores principales: Zhang, Yingchi, Lu, Rui, Huang, Xiaojian, Yin, Enzhi, Yang, Yong, Yi, Chengla, You, Hongbo, Song, Xianzhou, Yuan, Xuefeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9356867/
https://www.ncbi.nlm.nih.gov/pubmed/35992546
http://dx.doi.org/10.1155/2022/7614497

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9356867/
https://www.ncbi.nlm.nih.gov/pubmed/35992546
http://dx.doi.org/10.1155/2022/7614497

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