PCGF6 controls neuroectoderm specification of human pluripotent stem cells by activating SOX2 expression

Polycomb group (PcG) proteins are known to repress developmental genes during embryonic development and tissue homeostasis. Here, we report that PCGF6 controls neuroectoderm specification of human pluripotent stem cells (PSCs) by activating SOX2 gene. Human PSCs with PCGF6 depletion display impaired...

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Detalles Bibliográficos
Autores principales: Lan, Xianchun, Ding, Song, Zhang, Tianzhe, Yi, Ying, Li, Conghui, Jin, Wenwen, Chen, Jian, Liang, Kaiwei, Wang, Hengbin, Jiang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9357003/
https://www.ncbi.nlm.nih.gov/pubmed/35933409
http://dx.doi.org/10.1038/s41467-022-32295-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9357003/
https://www.ncbi.nlm.nih.gov/pubmed/35933409
http://dx.doi.org/10.1038/s41467-022-32295-z

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