Elevation of gangliosides in four brain regions from Parkinson’s disease patients with a GBA mutation

A number of genetic risk factors have been identified over the past decade for Parkinson’s Disease (PD), with variants in GBA prominent among them. GBA encodes the lysosomal enzyme that degrades the glycosphingolipid, glucosylceramide (GlcCer), with the activity of this enzyme defective in Gaucher d...

Descripción completa

Detalles Bibliográficos
Autores principales: Blumenreich, Shani, Nehushtan, Tamar, Barav, Or B., Saville, Jennifer T., Dingjan, Tamir, Hardy, John, Fuller, Maria, Futerman, Anthony H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9357011/
https://www.ncbi.nlm.nih.gov/pubmed/35933559
http://dx.doi.org/10.1038/s41531-022-00363-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9357011/
https://www.ncbi.nlm.nih.gov/pubmed/35933559
http://dx.doi.org/10.1038/s41531-022-00363-2

Ejemplares similares