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A single-cell atlas of the multicellular ecosystem of primary and metastatic hepatocellular carcinoma

Hepatocellular carcinoma (HCC) represents a paradigm of the relation between tumor microenvironment (TME) and tumor development. Here, we generate a single-cell atlas of the multicellular ecosystem of HCC from four tissue sites. We show the enrichment of central memory T cells (T(CM)) in the early t...

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Detalles Bibliográficos
Autores principales: Lu, Yiming, Yang, Aiqing, Quan, Cheng, Pan, Yingwei, Zhang, Haoyun, Li, Yuanfeng, Gao, Chengming, Lu, Hao, Wang, Xueting, Cao, Pengbo, Chen, Hongxia, Lu, Shichun, Zhou, Gangqiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9357016/
https://www.ncbi.nlm.nih.gov/pubmed/35933472
http://dx.doi.org/10.1038/s41467-022-32283-3