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A single-cell atlas of the multicellular ecosystem of primary and metastatic hepatocellular carcinoma
Hepatocellular carcinoma (HCC) represents a paradigm of the relation between tumor microenvironment (TME) and tumor development. Here, we generate a single-cell atlas of the multicellular ecosystem of HCC from four tissue sites. We show the enrichment of central memory T cells (T(CM)) in the early t...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9357016/ https://www.ncbi.nlm.nih.gov/pubmed/35933472 http://dx.doi.org/10.1038/s41467-022-32283-3 |