Molecular mechanism for the synchronized electrostatic coacervation and co-aggregation of alpha-synuclein and tau

Amyloid aggregation of α-synuclein (αS) is the hallmark of Parkinson’s disease and other synucleinopathies. Recently, Tau protein, generally associated with Alzheimer’s disease, has been linked to αS pathology and observed to co-localize in αS-rich disease inclusions, although the molecular mechanis...

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Detalles Bibliográficos
Autores principales: Gracia, Pablo, Polanco, David, Tarancón-Díez, Jorge, Serra, Ilenia, Bracci, Maruan, Oroz, Javier, Laurents, Douglas V., García, Inés, Cremades, Nunilo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9357037/
https://www.ncbi.nlm.nih.gov/pubmed/35933508
http://dx.doi.org/10.1038/s41467-022-32350-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9357037/
https://www.ncbi.nlm.nih.gov/pubmed/35933508
http://dx.doi.org/10.1038/s41467-022-32350-9

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