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Molecular mechanism for the synchronized electrostatic coacervation and co-aggregation of alpha-synuclein and tau
Amyloid aggregation of α-synuclein (αS) is the hallmark of Parkinson’s disease and other synucleinopathies. Recently, Tau protein, generally associated with Alzheimer’s disease, has been linked to αS pathology and observed to co-localize in αS-rich disease inclusions, although the molecular mechanis...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9357037/ https://www.ncbi.nlm.nih.gov/pubmed/35933508 http://dx.doi.org/10.1038/s41467-022-32350-9 |