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SETDB1 Restrains Endogenous Retrovirus Expression and Antitumor Immunity during Radiotherapy

The type I interferon response plays a pivotal role in promoting antitumor immune activity in response to radiotherapy. The identification of approaches to boost the radiation-induced type I interferon response could help improve the efficacy of radiotherapy. Here we show that the histone methyltran...

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Detalles Bibliográficos
Autores principales: Pan, Dong, Bao, Xuhui, Hu, Mengjie, Jiao, Meng, Li, Fang, Li, Chuan-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9357127/
https://www.ncbi.nlm.nih.gov/pubmed/35648422
http://dx.doi.org/10.1158/0008-5472.CAN-21-3523