Poor treatment responses were related to poor outcomes in pediatric B cell acute lymphoblastic leukemia with KMT2A rearrangements

BACKGROUND: The KMT2A gene, formerly named the MLL gene, is rearranged (KMT2Ar) in 70–75% of infants, 5–6% of children and 10–15% of adult patients with B cell acute lymphoblastic leukemia (B-ALL). The outcome after chemotherapy of pediatric cases remains poor, and only a few studies have investigat...

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Detalles Bibliográficos
Autores principales: Wen, Jinquan, Zhou, Min, Shen, Yali, long, Yueting, Guo, Yuxia, Song, Lin, Xiao, Jianwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9357304/
https://www.ncbi.nlm.nih.gov/pubmed/35933338
http://dx.doi.org/10.1186/s12885-022-09804-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9357304/
https://www.ncbi.nlm.nih.gov/pubmed/35933338
http://dx.doi.org/10.1186/s12885-022-09804-w

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