Effects of the administration of Elovl5-dependent fatty acids on a spino-cerebellar ataxia 38 mouse model

BACKGROUND: Spinocerebellar ataxia 38 (SCA38) is a rare autosomal neurological disorder characterized by ataxia and cerebellar atrophy. SCA38 is caused by mutations of ELOVL5 gene. ELOVL5 gene encodes a protein, which elongates long chain polyunsaturated fatty acids (PUFAs). Knockout mice lacking El...

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Detalles Bibliográficos
Autores principales: Balbo, Ilaria, Montarolo, Francesca, Genovese, Federica, Tempia, Filippo, Hoxha, Eriola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9357323/
https://www.ncbi.nlm.nih.gov/pubmed/35933444
http://dx.doi.org/10.1186/s12993-022-00194-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9357323/
https://www.ncbi.nlm.nih.gov/pubmed/35933444
http://dx.doi.org/10.1186/s12993-022-00194-4

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