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ELIMINATOR: essentiality analysis using multisystem networks and integer programming
A gene is considered as essential when it is indispensable for cells to grow and replicate in a certain environment. However, gene essentiality is not a structural property but rather a contextual one, which depends on the specific biological conditions affecting the cell. This circumstantial essent...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9357337/ https://www.ncbi.nlm.nih.gov/pubmed/35933325 http://dx.doi.org/10.1186/s12859-022-04855-z |