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In silico testing of flavonoids as potential inhibitors of protease and helicase domains of dengue and Zika viruses

BACKGROUND: Dengue and Zika are two major vector-borne diseases. Dengue causes up to 25,000 deaths and nearly a 100 million cases worldwide per year, while the incidence of Zika has increased in recent years. Although Zika has been associated to fetal microcephaly and Guillain-Barré syndrome both it...

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Detalles Bibliográficos
Autores principales: Cruz-Arreola, Omar, Orduña-Diaz, Abdu, Domínguez, Fabiola, Reyes-Leyva, Julio, Vallejo-Ruiz, Verónica, Domínguez-Ramírez, Lenin, Santos-López, Gerardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2022
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9357371/
https://www.ncbi.nlm.nih.gov/pubmed/35945938
http://dx.doi.org/10.7717/peerj.13650