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Generation of functional human oligodendrocytes from dermal fibroblasts by direct lineage conversion

Oligodendrocytes, the myelinating cells of the central nervous system, possess great potential for disease modeling and cell transplantation-based therapies for leukodystrophies. However, caveats to oligodendrocyte differentiation protocols ( Ehrlich et al., 2017; Wang et al., 2013; Douvaras and Fos...

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Detalles Bibliográficos
Autores principales: Tanabe, Koji, Nobuta, Hiroko, Yang, Nan, Ang, Cheen Euong, Huie, Philip, Jordan, Sacha, Oldham, Michael C., Rowitch, David H., Wernig, Marius
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9357374/
https://www.ncbi.nlm.nih.gov/pubmed/35748297
http://dx.doi.org/10.1242/dev.199723