MgIG exerts therapeutic effects on crizotinib‐induced hepatotoxicity by limiting ROS‐mediated autophagy and pyroptosis

Crizotinib (CRIZO) has been widely employed to treat non‐small‐cell lung cancer. However, hepatic inflammatory injury is the major toxicity of CRIZO, which limits its clinical application, and the underlying mechanism of CRIZO‐induced hepatotoxicity has not been fully explored. Herein, we used cell...

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Detalles Bibliográficos
Autores principales: Li, Min, Wang, Chenxiang, Yu, Zheng, Lan, Qin, Xu, Shaolin, Ye, Zhongjiang, Li, Rongqi, Ying, Lili, Zhang, Xiuhua, Zhou, Ziye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9357634/
https://www.ncbi.nlm.nih.gov/pubmed/35855570
http://dx.doi.org/10.1111/jcmm.17474

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9357634/
https://www.ncbi.nlm.nih.gov/pubmed/35855570
http://dx.doi.org/10.1111/jcmm.17474

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