Sildenafil improves radiation‐induced oral mucositis by attenuating oxidative stress, NF‐κB, ERK and JNK signalling pathways

Radiation‐induced oral mucositis is a common and dose‐limiting complication of head and neck radiotherapy with no effective treatment. Previous studies revealed that sildenafil, a phosphodiesterase 5 inhibitor, has anti‐inflammatory and anti‐cancer effects. In this study, we investigated the effect...

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Detalles Bibliográficos
Autores principales: Ala, Moein, Mohammad Jafari, Razieh, Ala, Mahan, Hejazi, Sedigheh Marjaneh, Tavangar, Seyed Mohammad, Mahdavi, Seied Rabi, Dehpour, Ahmad Reza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9357636/
https://www.ncbi.nlm.nih.gov/pubmed/35810384
http://dx.doi.org/10.1111/jcmm.17480

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9357636/
https://www.ncbi.nlm.nih.gov/pubmed/35810384
http://dx.doi.org/10.1111/jcmm.17480

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