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Resveratrol attenuates chronic pulmonary embolism-related endothelial cell injury by modulating oxidative stress, inflammation, and autophagy

OBJECTIVES: Due to Pulmonary Artery Endothelial Cell (PAEC) dysfunction, Pulmonary Hypertension (PH) persists even after the Pulmonary Embolism (PE) has been relieved. However, the mechanism behind this remains unclear. METHOD: Here, the authors incubated Human PAECs (HPAECs) with thrombin to simula...

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Detalles Bibliográficos
Autores principales: Liu, Xiaopeng, Zhou, Haiying, Hu, Zhixiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9357834/
https://www.ncbi.nlm.nih.gov/pubmed/35932505
http://dx.doi.org/10.1016/j.clinsp.2022.100083