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Pegcetacoplan in paroxysmal nocturnal hemoglobinuria: A systematic review on efficacy and safety

INTRODUCTION: Pegcetacoplan, a pegylated penta‐decapeptide, targets complement C3 to control both intravascular and extravascular hemolysis. This systematic review aims to study the efficacy and safety of pegcetacoplan in paroxysmal nocturnal hemoglobinuria (PNH). METHODS: We performed a comprehensi...

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Detalles Bibliográficos
Autores principales: Shah, Sangam, Chamlagain, Rajan, Musalman, Ziyaul Haq, Raj Adhikari, Yagya, Chhetri, Santosh, Paudel, Sujan, Gundabolu, Krishna, Dhakal, Prajwal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9357886/
https://www.ncbi.nlm.nih.gov/pubmed/35949886
http://dx.doi.org/10.1002/rth2.12781