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Baricitinib therapy response in rheumatoid arthritis patients associates to STAT1 phosphorylation in monocytes

Baricitinib is a Janus kinase (JAK) 1 and 2 inhibitor approved for treating rheumatoid arthritis (RA). The JAK/STAT system is essential in the intracellular signaling of different cytokines and in the activation process of the monocyte lineage. This study verifies the effects of baricitinib on STAT...

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Detalles Bibliográficos
Autores principales: Tucci, Gloria, Garufi, Cristina, Pacella, Ilenia, Zagaglioni, Marta, Pinzon Grimaldos, Alessandra, Ceccarelli, Fulvia, Conti, Fabrizio, Spinelli, Francesca Romana, Piconese, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9357974/
https://www.ncbi.nlm.nih.gov/pubmed/35958600
http://dx.doi.org/10.3389/fimmu.2022.932240