Cargando…
Baricitinib therapy response in rheumatoid arthritis patients associates to STAT1 phosphorylation in monocytes
Baricitinib is a Janus kinase (JAK) 1 and 2 inhibitor approved for treating rheumatoid arthritis (RA). The JAK/STAT system is essential in the intracellular signaling of different cytokines and in the activation process of the monocyte lineage. This study verifies the effects of baricitinib on STAT...
Autores principales: | Tucci, Gloria, Garufi, Cristina, Pacella, Ilenia, Zagaglioni, Marta, Pinzon Grimaldos, Alessandra, Ceccarelli, Fulvia, Conti, Fabrizio, Spinelli, Francesca Romana, Piconese, Silvia |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9357974/ https://www.ncbi.nlm.nih.gov/pubmed/35958600 http://dx.doi.org/10.3389/fimmu.2022.932240 |
Ejemplares similares
-
ISG15 protects human Tregs from interferon alpha‐induced contraction in a cell‐intrinsic fashion
por: Pacella, Ilenia, et al.
Publicado: (2020) -
Tapering and discontinuation of glucocorticoids in patients with rheumatoid arthritis treated with tofacitinib
por: Spinelli, Francesca Romana, et al.
Publicado: (2023) -
Reduction in regulatory T cells in preterm newborns is associated with necrotizing enterocolitis
por: Pacella, Ilenia, et al.
Publicado: (2023) -
Immunometabolic Checkpoints of Treg Dynamics: Adaptation to Microenvironmental Opportunities and Challenges
por: Pacella, Ilenia, et al.
Publicado: (2019) -
RNA Flow Cytometry for the Study of T Cell Metabolism
por: Rossi, Alessandra, et al.
Publicado: (2021)