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Biochemical, biophysical, and functional characterisation of the E3 ubiquitin ligase APC/C regulator CDC20 from Arabidopsis thaliana

The Anaphase Promoting Complex (APC/C), a large cullin-RING E3-type ubiquitin ligase, constitutes the ultimate target of the Spindle Assembly Checkpoint (SAC), an intricate regulatory circuit that ensures the high fidelity of chromosome segregation in eukaryotic organisms by delaying the onset of an...

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Detalles Bibliográficos
Autores principales: Cosma, Maria-Alexa, Curtis, Natalie L., Pain, Charlotte, Kriechbaumer, Verena, Bolanos-Garcia, Victor M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9357983/
https://www.ncbi.nlm.nih.gov/pubmed/35957989
http://dx.doi.org/10.3389/fphys.2022.938688