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ORFV infection enhances CXCL16 secretion and causes oncolysis of lung cancer cells through immunogenic apoptosis

Oncolytic viruses have been emerging as a promising therapeutic option for cancer patients, including lung cancer. Orf virus (ORFV), a DNA parapoxvirus, can infect its natural ungulate hosts and transmit into humans. Moreover, the ORFV has advantages of low toxicity, high targeted, self-amplificatio...

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Detalles Bibliográficos
Autores principales: Wang, Ruixue, Mo, Jingying, Luo, Xiaoshan, Zhang, Guixian, Liu, Fang, Luo, Shuhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9358046/
https://www.ncbi.nlm.nih.gov/pubmed/35959371
http://dx.doi.org/10.3389/fcimb.2022.910466