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Single‐cell transcriptomics reveals a senescence‐associated IL‐6/CCR6 axis driving radiodermatitis

Irradiation‐induced alopecia and dermatitis (IRIAD) are two of the most visually recognized complications of radiotherapy, of which the molecular and cellular basis remains largely unclear. By combining scRNA‐seq analysis of whole skin‐derived irradiated cells with genetic ablation and molecular inh...

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Detalles Bibliográficos
Autores principales: Paldor, Mor, Levkovitch‐Siany, Orr, Eidelshtein, Dana, Adar, Revital, Enk, Claes D, Marmary, Yitzhak, Elgavish, Sharona, Nevo, Yuval, Benyamini, Hadar, Plaschkes, Inbar, Klein, Shiri, Mali, Alex, Rose‐John, Stefan, Peled, Amnon, Galun, Eithan, Axelrod, Jonathan H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9358397/
https://www.ncbi.nlm.nih.gov/pubmed/35785521
http://dx.doi.org/10.15252/emmm.202115653