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Alteration of microbiota antibody‐mediated immune selection contributes to dysbiosis in inflammatory bowel diseases

Human secretory immunoglobulins (SIg) A1 and SIgA2 guide mucosal responses toward tolerance or inflammation, notably through reverse‐transcytosis, the apical‐to‐basal transport of IgA2 immune complexes via M cells of gut Peyer's patches. As such, the maintenance of a diverse gut microbiota requ...

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Detalles Bibliográficos
Autores principales: Michaud, Eva, Waeckel, Louis, Gayet, Rémi, Goguyer‐Deschaumes, Roman, Chanut, Blandine, Jospin, Fabienne, Bathany, Katell, Monnoye, Magali, Genet, Coraline, Prier, Amelie, Tokarski, Caroline, Gérard, Philippe, Roblin, Xavier, Rochereau, Nicolas, Paul, Stéphane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9358401/
https://www.ncbi.nlm.nih.gov/pubmed/35785473
http://dx.doi.org/10.15252/emmm.202115386