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Endoplasmic reticulum stress triggered autophagy and regulated the phenotype transformation of rheumatoid arthritis synovial fibroblasts via the IRE1/JNK pathway

BACKGROUND: Previous studies have indicated that endoplasmic reticulum (ER) stress may actively promote the pathogenesis of rheumatoid arthritis (RA) by evoking autophagy. However, the underlying mechanism remains largely unknown. This study aimed to explore the mechanism of the ER stress-autophagy...

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Detalles Bibliográficos
Autores principales: Wang, Liujun, Fan, Yong, Gui, Yanni, Yang, Xinlei, Ye, Xia, Cao, Yongping, Zhang, Zhuoli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9358491/
https://www.ncbi.nlm.nih.gov/pubmed/35957705
http://dx.doi.org/10.21037/atm-22-15