Cargando…

Endoplasmic reticulum stress triggered autophagy and regulated the phenotype transformation of rheumatoid arthritis synovial fibroblasts via the IRE1/JNK pathway

BACKGROUND: Previous studies have indicated that endoplasmic reticulum (ER) stress may actively promote the pathogenesis of rheumatoid arthritis (RA) by evoking autophagy. However, the underlying mechanism remains largely unknown. This study aimed to explore the mechanism of the ER stress-autophagy...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Liujun, Fan, Yong, Gui, Yanni, Yang, Xinlei, Ye, Xia, Cao, Yongping, Zhang, Zhuoli
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AME Publishing Company 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9358491/ https://www.ncbi.nlm.nih.gov/pubmed/35957705 http://dx.doi.org/10.21037/atm-22-15

Ejemplares similares

Connecting endoplasmic reticulum stress to autophagy through IRE1/JNK/beclin-1 in breast cancer cells
por: Cheng, Xiu, et al.
Publicado: (2021)

Association of autophagy to the phenotypic transformation of synovial fibroblasts in rheumatoid arthritis
por: Kondo, Naoki
Publicado: (2022)

Endoplasmic reticulum stress triggers Xanthoangelol-induced protective autophagy via activation of JNK/c-Jun Axis in hepatocellular carcinoma
por: Li, Zichao, et al.
Publicado: (2019)

IRE1β negatively regulates IRE1α signaling in response to endoplasmic reticulum stress
por: Grey, Michael J., et al.
Publicado: (2020)

IRE1α is an endogenous substrate of endoplasmic reticulum-associated degradation
por: Sun, Shengyi, et al.
Publicado: (2015)

EDEM1 regulates the insulin mRNA level by inhibiting the endoplasmic reticulum stress-induced IRE1/JNK/c-Jun pathway
por: (Flintoaca) Alexandru, Petruta R., et al.
Publicado: (2023)

Retraction Note: Endoplasmic reticulum stress triggers Xanthoangelol-induced protective autophagy via activation of JNK/c-Jun Axis in hepatocellular carcinoma
por: Li, Zichao, et al.
Publicado: (2020)

Homeostatic adaptation to endoplasmic reticulum stress depends on Ire1 kinase activity
por: Rubio, Claudia, et al.
Publicado: (2011)

Inositol Requiring Enzyme (IRE), a multiplayer in sensing endoplasmic reticulum stress
por: Zhou, Zhixin, et al.
Publicado: (2022)

Asiatic Acid Induces Endoplasmic Reticulum Stress and Activates the Grp78/IRE1α/JNK and Calpain Pathways to Inhibit Tongue Cancer Growth
por: Li, Jialin, et al.
Publicado: (2021)

Oxidized lipids activate autophagy in a JNK-dependent manner by stimulating the endoplasmic reticulum stress response()
por: Haberzettl, Petra, et al.
Publicado: (2013)

Autophagy induction and CHOP under-expression promotes survival of fibroblasts from rheumatoid arthritis patients under endoplasmic reticulum stress
por: Shin, Yong-Joo, et al.
Publicado: (2010)

4-Hydroxyisoleucine inhibits tumor growth by triggering endoplasmic reticulum stress and autophagy
por: Li, Peng, et al.
Publicado: (2022)

IRES-Dependent Translational Control during Virus-Induced Endoplasmic Reticulum Stress and Apoptosis
por: Hanson, Paul J., et al.
Publicado: (2012)

Iron affects Ire1 clustering propensity and the amplitude of endoplasmic reticulum stress signaling
por: Cohen, Nir, et al.
Publicado: (2017)

Endoplasmic Reticulum Stress Is Involved in Stress-Induced Hypothalamic Neuronal Injury in Rats via the PERK-ATF4-CHOP and IRE1-ASK1-JNK Pathways
por: Yi, Shanyong, et al.
Publicado: (2019)

Arsenic trioxide potentiates Gilteritinib-induced apoptosis in FLT3-ITD positive leukemic cells via IRE1a-JNK-mediated endoplasmic reticulum stress
por: Hu, Xiaoli, et al.
Publicado: (2020)

Dimethyl fumarate abrogates striatal endoplasmic reticulum stress in experimentally induced late-stage Huntington’s disease: Focus on the IRE1α/JNK and PERK/CHOP trajectories
por: Hassab, Lina Y., et al.
Publicado: (2023)

Activation of Synovial Fibroblasts in Rheumatoid Arthritis
por: Gay, Steffen, et al.
Publicado: (2000)

A role for BiP as an adjustor for the endoplasmic reticulum stress-sensing protein Ire1
por: Kimata, Yukio, et al.
Publicado: (2004)

Transdifferentiation mediated tumor suppression by the endoplasmic reticulum stress sensor IRE-1 in C. elegans
por: Levi-Ferber, Mor, et al.
Publicado: (2015)

IRE1α Implications in Endoplasmic Reticulum Stress-Mediated Development and Pathogenesis of Autoimmune Diseases
por: Junjappa, Raghu Patil, et al.
Publicado: (2018)

Probing natural variation of IRE1 expression and endoplasmic reticulum stress responses in Arabidopsis accessions
por: Afrin, Taiaba, et al.
Publicado: (2020)

L-Ascorbic Acid Inhibits Breast Cancer Growth by Inducing IRE/JNK/CHOP-Related Endoplasmic Reticulum Stress-Mediated p62/SQSTM1 Accumulation in the Nucleus
por: Choi, Youn Kyung, et al.
Publicado: (2020)

Magnetite Fe(3)O(4) Nanoparticles Enhance Mild Microwave Ablation of Tumor by Activating the IRE1-ASK1-JNK Pathway and Inducing Endoplasmic Reticulum Stress
por: Li, Shuai, et al.
Publicado: (2021)

The endoplasmic reticulum stress induced by tunicamycin affects the viability and autophagy activity of chondrocytes
por: Wu, Hao, et al.
Publicado: (2020)

Atlastins remodel the endoplasmic reticulum for selective autophagy
por: Liang, Jin Rui, et al.
Publicado: (2018)

ER‐phagy: selective autophagy of the endoplasmic reticulum
por: Mochida, Keisuke, et al.
Publicado: (2022)

HMGB1–LPS complex promotes transformation of osteoarthritis synovial fibroblasts to a rheumatoid arthritis synovial fibroblast-like phenotype
por: Qin, Y, et al.
Publicado: (2014)

Coxsackievirus B3 Infection Triggers Autophagy through 3 Pathways of Endoplasmic Reticulum Stress
por: LUO, Xiao Nuan, et al.
Publicado: (2018)

Membrane aberrancy and unfolded proteins activate the endoplasmic reticulum stress sensor Ire1 in different ways
por: Promlek, Thanyarat, et al.
Publicado: (2011)

In vitro FRET analysis of IRE1 and BiP association and dissociation upon endoplasmic reticulum stress
por: Kopp, Megan C, et al.
Publicado: (2018)

Caspase-mediated cleavage of IRE1 controls apoptotic cell commitment during endoplasmic reticulum stress
por: Shemorry, Anna, et al.
Publicado: (2019)

The unfolded protein response and endoplasmic reticulum protein targeting machineries converge on the stress sensor IRE1
por: Acosta-Alvear, Diego, et al.
Publicado: (2018)

The ADP-binding kinase region of Ire1 directly contributes to its responsiveness to endoplasmic reticulum stress
por: Le, Quynh Giang, et al.
Publicado: (2021)

A Molecular Mechanism for Turning Off IRE1α Signaling during Endoplasmic Reticulum Stress
por: Li, Xia, et al.
Publicado: (2020)

Decoding non-canonical mRNA decay by the endoplasmic-reticulum stress sensor IRE1α
por: Le Thomas, Adrien, et al.
Publicado: (2021)

IRE1/XBP1 and endoplasmic reticulum signaling — from basic to translational research for cardiovascular disease
por: Fu, Fangyi, et al.
Publicado: (2022)

Fibroblast biology: Role of synovial fibroblasts in the pathogenesis of rheumatoid arthritis
por: Pap, Thomas, et al.
Publicado: (2000)

Cells of the synovium in rheumatoid arthritis. Synovial fibroblasts
por: Müller-Ladner, Ulf, et al.
Publicado: (2007)

Cannot write session to /tmp/vufind_sessions/sess_6073fn57ct1d9hhokifec19gd5