Selenium substituted axitinib reduces axitinib side effects and maintains its anti-renal tumor activity

Axitinib is a potent vascular endothelial growth factor receptor (VEGFR) inhibitor, which has a strong inhibitory effect on the three isoforms of VEGFR 1–3. Having strong therapeutic efficacy, its broad use is limited by its side effects such as hypertension, proteinuria, cardiovascular damage, and...

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Detalles Bibliográficos
Autores principales: Fu, Ying, Saxu, Rengui, Ahmad Ridwan, Kadir, Zhao, Cai, Kong, Xiangshun, Rong, Yao, Zheng, Weida, Yu, Peng, Teng, Yuou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9358677/
https://www.ncbi.nlm.nih.gov/pubmed/36043080
http://dx.doi.org/10.1039/d2ra01882a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9358677/
https://www.ncbi.nlm.nih.gov/pubmed/36043080
http://dx.doi.org/10.1039/d2ra01882a

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