Kinetic profiling and functional characterization of 8-phenylxanthine derivatives as A(2B) adenosine receptor antagonists

A(2B) adenosine receptor (A(2B)AR) antagonists have therapeutic potential in inflammation-related diseases such as asthma, chronic obstructive pulmonary disease and cancer. However, no drug is currently clinically approved, creating a demand for research on novel antagonists. Over the last decade, t...

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Detalles Bibliográficos
Autores principales: Vlachodimou, Anna, de Vries, Henk, Pasoli, Milena, Goudswaard, Miranda, Kim, Soon-Ai, Kim, Yong-Chul, Scortichini, Mirko, Marshall, Melissa, Linden, Joel, Heitman, Laura H., Jacobson, Kenneth A., IJzerman, Adriaan P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9358681/
https://www.ncbi.nlm.nih.gov/pubmed/35395239
http://dx.doi.org/10.1016/j.bcp.2022.115027

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9358681/
https://www.ncbi.nlm.nih.gov/pubmed/35395239
http://dx.doi.org/10.1016/j.bcp.2022.115027

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