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Structural basis for acyl chain control over glycosphingolipid sorting and vesicular trafficking
The complex sphingolipids exhibit a diversity of ceramide acyl chain structures that influence their trafficking and intracellular distributions, but it remains unclear how the cell discerns among the different ceramides to affect such sorting. To address the mechanism, we synthesize a library of GM...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9358721/ https://www.ncbi.nlm.nih.gov/pubmed/35830800 http://dx.doi.org/10.1016/j.celrep.2022.111063 |