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Transcriptome analysis of immune cells from Behçet’s syndrome patients: the importance of IL-17-producing cells and antigen-presenting cells in the pathogenesis of Behçet’s syndrome

BACKGROUND: Behçet’s syndrome (BS) is an immune-mediated disease characterized by recurrent oral ulcers, genital ulcers, uveitis, and skin symptoms. HLA-B51, as well as other genetic polymorphisms, has been reported to be associated with BS; however, the pathogenesis of BS and its relationship to ge...

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Detalles Bibliográficos
Autores principales: Okubo, Mai, Sumitomo, Shuji, Tsuchida, Yumi, Nagafuchi, Yasuo, Takeshima, Yusuke, Yanaoka, Haruyuki, Shirai, Harumi, Kobayashi, Satomi, Sugimori, Yusuke, Maeda, Junko, Hatano, Hiroaki, Iwasaki, Yukiko, Shoda, Hirofumi, Okamura, Tomohisa, Yamamoto, Kazuhiko, Ota, Mineto, Fujio, Keishi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9358821/
https://www.ncbi.nlm.nih.gov/pubmed/35941595
http://dx.doi.org/10.1186/s13075-022-02867-x