The tyrosine capsid mutations on retrograde adeno-associated virus accelerates gene transduction efficiency

Adeno-associated virus (AAV) vector is a critical tool for gene delivery through its durable transgene expression and safety profile. Among many serotypes, AAV2-retro is typically utilized for dissecting neural circuits with its retrograde functionality. However, this vector requires a relatively lo...

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Detalles Bibliográficos
Autores principales: Nakahama, Ryota, Saito, Aika, Nobe, Sensho, Togashi, Kazuya, Suzuki, Ikuo K., Uematsu, Akira, Emoto, Kazuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9358834/
https://www.ncbi.nlm.nih.gov/pubmed/35941689
http://dx.doi.org/10.1186/s13041-022-00957-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9358834/
https://www.ncbi.nlm.nih.gov/pubmed/35941689
http://dx.doi.org/10.1186/s13041-022-00957-0

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