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The tyrosine capsid mutations on retrograde adeno-associated virus accelerates gene transduction efficiency

Adeno-associated virus (AAV) vector is a critical tool for gene delivery through its durable transgene expression and safety profile. Among many serotypes, AAV2-retro is typically utilized for dissecting neural circuits with its retrograde functionality. However, this vector requires a relatively lo...

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Detalles Bibliográficos
Autores principales:	Nakahama, Ryota, Saito, Aika, Nobe, Sensho, Togashi, Kazuya, Suzuki, Ikuo K., Uematsu, Akira, Emoto, Kazuo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9358834/ https://www.ncbi.nlm.nih.gov/pubmed/35941689 http://dx.doi.org/10.1186/s13041-022-00957-0

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