Impact of a conserved N-terminal proline-rich region of the α-subunit of CAAX-prenyltransferases on their enzyme properties

BACKGROUND: The CAAX-prenyltransferases farnesyltransferase (FTase) and geranylgeranyltransferase I (GGTase I) are heterodimers with a common α- (FTα) and unique β-subunits. Recently, α-subunits of species (e.g., human) that harbour an N-terminal proline-rich region (PRR) showed different dimerizati...

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Detalles Bibliográficos
Autores principales: Hagemann, Anna, Tasillo, Sandro, Aydin, Aykut, Kehrenberg, Miriam Caroline Alice, Bachmann, Hagen Sjard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9358863/
https://www.ncbi.nlm.nih.gov/pubmed/35941619
http://dx.doi.org/10.1186/s12964-022-00929-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9358863/
https://www.ncbi.nlm.nih.gov/pubmed/35941619
http://dx.doi.org/10.1186/s12964-022-00929-w

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