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Regulation of type I interferon signature by VGLL3 in the fibroblast-like synoviocytes of rheumatoid arthritis patients via targeting the Hippo pathway

BACKGROUND: The upregulation of interferon (IFN)-stimulated genes induced by type I IFNs (namely type I IFN signature) in rheumatoid arthritis (RA) patients had implications in early diagnosis and prediction of therapy responses. However, factors that modulate the type I IFN signature in RA are larg...

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Detalles Bibliográficos
Autores principales: Du, Yu, Cui, Ran, Tian, Na, Chen, Miao, Zhang, Xian-Long, Dai, Sheng-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9358906/
https://www.ncbi.nlm.nih.gov/pubmed/35941675
http://dx.doi.org/10.1186/s13075-022-02880-0