Pharmacomodulation of a ligand targeting the HBV capsid hydrophobic pocket

Hepatitis B virus (HBV) is a small enveloped retrotranscribing DNA virus and an important human pathogen. Its capsid-forming core protein (Cp) features a hydrophobic pocket proposed to be central notably in capsid envelopment. Indeed, mutations in and around this pocket can profoundly modulate, and...

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Detalles Bibliográficos
Autores principales: Briday, Mathilde, Hallé, François, Lecoq, Lauriane, Radix, Sylvie, Martin, Juliette, Montserret, Roland, Dujardin, Marie, Fogeron, Marie-Laure, Nassal, Michael, Meier, Beat H., Lomberget, Thierry, Böckmann, Anja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9358932/
https://www.ncbi.nlm.nih.gov/pubmed/36042894
http://dx.doi.org/10.1039/d2sc02420a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9358932/
https://www.ncbi.nlm.nih.gov/pubmed/36042894
http://dx.doi.org/10.1039/d2sc02420a

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