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Stereochemical course of cobalamin-dependent radical SAM methylation by TokK and ThnK
Complex carbapenems are important clinical antibiotics for difficult-to-treat infections. An essential step in the biosyntheses of these natural products is stereospecific methylation at C6 and subsequent alkylations by cobalamin-dependent radical SAM methylases such as TokK and ThnK. We have prepar...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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RSC
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9358933/ https://www.ncbi.nlm.nih.gov/pubmed/36042702 http://dx.doi.org/10.1039/d2cb00113f |